Philosophy Lexicon of Arguments

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Information, information theory: A character or a character combination contains information when it is clear to the recipient that this character or the character combination appears instead of another possible character or a possible character combination. The supply of possible characters determines to a part the probability of the occurrence of a character from this supply. In addition, the expected probability of the appearance of a character can be increased by already experienced experiences of regularities. The amount of information transmitted by a character depends on the improbability of the occurrence of the character.

Annotation: The above characterizations of concepts are neither definitions nor exhausting presentations of problems related to them. Instead, they are intended to give a short introduction to the contributions below. – Lexicon of Arguments.

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I 111
Order/Life/Human/Kauffman: the human is the product of two sources of order, not one.
I 112
Information/order/life/emergence/Kauffman: most people assume that DNA and RNA are stable stores of genetic information. However, if life began with collective autocatalysis and later learned to incorporate DNA and genetic code, we must explain how these formations could be subject to hereditary variation and natural selection, even though they did not yet contain a genome!
On the one hand, evolution cannot proceed without matrices copying mechanisms, but on the other hand it is the one that combines the mechanisms.
Could an autocatalytic formation evolve without it?
Solution: Spatial compartments (spaces divided by membranes) that split are capable of variation and evolution!
Solution: Assumption: every now and then random, uncatalysed reactions take place and produce new molecules. The metabolism (conversion, metabolism) would be extended by a reaction loop.
Evolution without genome, no DNA-like structure as a carrier of information.
I 114
Catalysis/Autocatalysis/Kauffman: in the case of autocatalytic formations, there is no difference between genotype and phenotype.
Life/emergence/Kauffman: this inevitably leads to the formation of a complex ecosystem. Molecules produced in a primordial cell can be transported into other primordial cells and influence reactions there.
Metabolic-based life does not arise as a whole or as a complex structure, but the entire spectrum of mutualism and competition is present from the very beginning. Not only evolution, but also co-evolution.
I 115
Order/life/emergence/Kauffman: the autocatalytic formations must coordinate the behaviour of several thousand molecules. The potential chaos is beyond imagination. Therefore, another source of molecular order has to be discovered, the fundamental internal homeostasis (balance). Surprisingly simple boundary conditions are sufficient for this.
- - -
I 148
Information/Genes/Kauffman: Question: What mechanism controls the implementation and suppression of certain genetic information? And how do the different cell types know which genes to use and when?
J. Monod/Francois Jacob: Mid-1960s: Discovery of an operator that only releases a reaction at a certain point in time.
I 149
Also repressor. A small molecule can "switch on" a gene.
I 150
In the simplest case, two genes can suppress each other. Two possible patterns.
Gene 1 is active and suppresses gene 2 or vice versa.
Both cell types would then have the same "genotype", the same genome, but they could realize different gene sets.
New horizon of knowledge: unexpected and far-reaching freedom at the molecular level.
The addition of the repressor to the operator at different points results in different receptivity to the operator on the DNA. Regulation.
I 151
This control mechanism by addition in two different places means complete freedom for the molecules to create genetic circuits of arbitrary logic and complexity.
We must first learn to understand such systems.

Explanation of symbols: Roman numerals indicate the source, arabic numerals indicate the page number. The corresponding books are indicated on the right hand side. ((s)…): Comment by the sender of the contribution.

Kau I
St. Kauffman
Der Öltropfen im Wasser München 1998

Kau II
Stuart Kauffman
At Home in the Universe: The Search for the Laws of Self-Organization and Complexity

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Ed. Martin Schulz, access date 2018-03-19