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Molecular Genetics on Heritability - Dictionary of Arguments

Slater I 127
Heritability/molecular genetics: Genome-wide association studies of cognitive ability test scores have yielded many alleles of extremely small effects that tend not to replicate from sample to sample and account at best for only tiny proportions of trait variance. At present we have not yet identified a single gene locus robustly associated with normal range cognitive ability test scores (Davis, Butcher, Docherty, Meaburn, & Curtis, 2010(1); Deary, Penke, & Johnson, 2010)(2). The general failure to identify clear associations between particular gene loci and highly heritable, well-measured common traits has been termed the “missing heritability problem” (Maher, 2008)(3). [There are] more complex genetic mechanisms (see Johnson, Penke, & Spinath, 2011(4), for more detailed information).



1. Davis, O. S., Butcher, L. M., Docherty, S. J., Meaburn, E. L., & Curtis, C. J. (2010). A three-stage genome-wide association study of general cognitive ability: Hunting the small effects. Behavior Genetics, 40, 759–767.
2. Deary, I. J., Penke, L., & Johnson, W. (2010). The neuroscience of human intelligence differences. Nature Reviews Neuroscience, 11, 201–211.
3 .Maher, B. (2008). The case of the missing heritaiblity. Nature, 456, 18–21.
4. Johnson, W., Penke, L., & Spinath, F. M. (2011). Heritability in the era of molecular genetics. European Journal of Personality, 25, 254–266.



Wendy Johnson: „How Much Can We Boost IQ? Updated Look at Jensen’s (1969) Question and Answer“, in: Alan M. Slater & Paul C. Quinn (eds.) 2012. Developmental Psychology. Revisiting the Classic Studies. London: Sage Publications


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The note [Author1]Vs[Author2] or [Author]Vs[term] is an addition from the Dictionary of Arguments. If a German edition is specified, the page numbers refer to this edition.
Molecular Genetics
Slater I
Alan M. Slater
Paul C. Quinn
Developmental Psychology. Revisiting the Classic Studies London 2012


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